Evaluation of indirect sequence-specific magneto-extraction-aided LAMP for fluorescence and electrochemical SARS-CoV-2 nucleic acid detectionArticle Published on 2023-01-152022-11-15 Journal: Talanta [Category] SARS, 변종, 치료기술, 치료제, [키워드] amplification approach circumvent clinically Disadvantages Electrochemical LAMP Host in silico inhibitor investigated isothermal isothermal amplification Magnetic sequence-specific target enrichment molecular NAAT nucleic acid Nucleic acid detection PCR polymerase probe qRT-PCR Quantitative Quantitative real-time LAMP real-time reverse transcriptase restrict SARS-CoV-2 SARS-CoV-2 nucleic acid SARS-CoV-2 variant SARS-CoV-2. sensitivity sequence serum turn [DOI] 10.1016/j.talanta.2022.123809 PMC 바로가기
Current trends in COVID-19 diagnosis and its new variants in physiological fluids: Surface antigens, antibodies, nucleic acids, and RNA sequencingReview article Published on 2022-12-012022-10-05 Journal: TrAC Trends in Analytical Chemistry [Category] 바이오마커, 변종, 진단, 치료기술, [키워드] addressed antibodies antibody Antigen antigens Beta Biomarker biosensors Blood body fluid circulation clustered regularly interspaced short palindromic repeats COVID-19 COVID-19 diagnosis COVID-19 virus diagnosis CRISPR Critical current Delta Detection sensitivity diagnostic early stage ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay Gamma Infection isothermal amplification lateral flow immunoassay LFIA limit Loop-mediated isothermal amplification microarray analysis Microarray assays Mutation nucleic acid nucleic acids omicron outbreak overcome palindromic repeat physiological provide Rapid reduce reverse transcriptase-polymerase chain reaction reverse transcription RNA sequencing RT-LAMP RT-PCR Saliva SARS-CoV-2 Semen specificity Spread surface Urine variant variants virus viruses [DOI] 10.1016/j.trac.2022.116750 [Article Type] Review article
Ultrasensitive monitoring of SARS-CoV-2-specific antibody responses based on a digital approach reveals one week of IgG seroconversionArticle Published on 2022-12-012022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] addition antibodies Antibody Response approach AUC collected COVID-19 COVID-19 patient diagnostic diagnostics Donor Extreme early-stage seroconversion faster flow cytometry healthy IgG IgG and IgM IgG/IgM antibodies IgM immunoassay immunoassays immunological inactivated nucleic acid nucleic acids other diseases pathogen-specific Patient peptide platform probe Protein RBD reveal Rhesus monkeys SARS-CoV-2 S2 sensitivity Seroconversion seroconversion time Simoa tested Ultrasensitive digital detection. vaccination virus wild-type [DOI] 10.1016/j.bios.2022.114710 PMC 바로가기
Nanozyme-strip for rapid and ultrasensitive nucleic acid detection of SARS-CoV-2Article Published on 2022-12-012022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome amplification amplify catalytic clinical sample coronavirus coronavirus disease COVID-19 develop Diagnosis gold standard highlighting HPV-16 limit of detection Nanozyme strips nontoxic nucleic acid nucleic acid amplification Nucleic acid detection pandemic POCT point-of-care point-of-care testing polymerase REcombinase recombinase polymerase amplification reliability RPA RT-PCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2. subsequent TMB unique viral infections virus [DOI] 10.1016/j.bios.2022.114739 PMC 바로가기
Clinical microbiology in detection and identification of emerging microbial pathogens: past, present and futureArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] 진단, [키워드] Antibody assays Antigen Bacterial pathogens change clinical clinical microbiology Clinical practice COVID-19 COVID-19 pandemic Critical Culture Diagnosis diagnostics Diseases evidenced Genomics Gram stain IMPROVE in vitro Infectious disease metabolomics microbial microbial infections Molecular biology MONITOR morphology nucleic acid nucleic acid amplification outcome pathogen detection Patient point of care progression proteomics Revolutionary transcriptomics transcriptomics. [DOI] 10.1080/22221751.2022.2125345 PMC 바로가기
Statistical analysis supports UTR (untranslated region) deletion theory in SARS-CoV-2Article Published on 2022-12-012022-11-16 Journal: Virulence [Category] COVID19(2023년), SARS, 변종, [키워드] affected Analysis ancestor Asymptomatic asymptomatic patients clinical outcomes correlation Degradation deletion of the untranslated region demonstrated Deterioration driving early stage evaluate Evolution explain genetic influence Genome hospitalized patient indicated mathematical Mortality mortality rate Mutation nucleic acid nucleic acid degradation system Patient SARS-CoV-2 SARS-COV-2 infection significantly significantly more similarity strain Support Symptoms the epidemic Toxicity UTR viral genome viral toxicity viral toxicity. virulence virus virus genome was performed [DOI] 10.1080/21505594.2022.2132059 PMC 바로가기
Recent advances in applying G-quadruplex for SARS-CoV-2 targeting and diagnosis: A reviewArticle Published on 2022-11-302022-11-15 Journal: International journal of biological macromolecules [Category] SARS, 변종, 치료기술, 치료제, [키워드] accumulating addressed antiviral drug Care caused coronavirus SARS-CoV-2 diagnostic functions G-quadruplex Health Host Immune escape Intervention Ligand ligands neutralizing antibody nucleic acid pandemic polymerases protease Protein question recent regulate SARS-CoV-2 SARS-CoV-2 detection Structure targeting Targeting. Treatment strategies Vaccine variant virus virus [DOI] 10.1016/j.ijbiomac.2022.09.152 PMC 바로가기
Aptasensors for the detection of infectious pathogens: design strategies and point-of-care testingArticle Published on 2022-11-092022-11-15 Journal: Mikrochimica Acta [Category] 치료기술, 치료제, [키워드] approaches aptasensors Bacteria caused contagious coronavirus disease COVID-19 Critical Diagnosis diagnostics Diseases employment Epidemic highlighting implementation Infectious disease infectious pathogens life-threatening mechanisms Nanomaterial-based biosensors nucleic acid pathogen Perspective platform POCT point-of-care Point-of-care testing. Pressing prevalent provided target pathogen viruses [DOI] 10.1007/s00604-022-05533-w PMC 바로가기
A Rapid SARS-CoV-2 Nucleocapsid Protein Profiling Assay with High Sensitivity Comparable to Nucleic Acid DetectionArticle Published on 2022-10-252022-11-15 Journal: Analytical Chemistry [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acid Antigen binding caused Concentration COVID-19 COVID-19 diagnosis detection DNA effective ELISA kits Epidemic Epidemics information limit of detection magnitude N protein nucleic acid nucleocapsid protein PCR Profiling Protein Rapid Region resulting Saliva SARS-CoV-2 sensitivity target protein The fluorescence intensity the N protein translation [DOI] 10.1021/acs.analchem.2c02670 PMC 바로가기
Forty Years of Molecular Diagnostics for Infectious DiseasesArticle Published on 2022-10-192022-11-15 Journal: Journal of Clinical Microbiology [Category] 유전자 메커니즘, 진단, 치료기술, [키워드] amplification assumed Care coronavirus disease COVID-19 detect diagnostic diagnostic molecular microbiology diagnostics DNA DNA sequencing elapsed Factors Health in vitro Infectious disease Intersection knowledge Magnetic beads microbial molecular nucleic acid nucleic acids nucleotide nucleotide array pandemic pathophysiologic PCR Perspective point of care progression quantification Quantitative real-time quantitative PCR Sequencing syndromic panel. turn Year [DOI] 10.1128/jcm.02446-21 PMC 바로가기